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Overcoming the On‐Target Toxicity in Antibody‐Mediated Therapies via an Indirect Active Targeting Strategy
Antibody‐based therapies could be led astray when target receptors are expressed on nontarget sites, and the on‐target toxicity poses critical challenges to clinical applications. Here, a biomimetic indirect active targeting (INTACT) strategy is proposed based on receptor expression disparities betw...
Autores principales: | Tang, Zhongjie, Wang, Xiaoyou, Tang, Mei, Wu, Jin, Zhang, Jiexuan, Liu, Xinlong, Gao, Feiyan, Fu, Yu, Tang, Peng, Li, Chong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037698/ https://www.ncbi.nlm.nih.gov/pubmed/36683161 http://dx.doi.org/10.1002/advs.202206912 |
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