Mediation effects of DNA methylation and hydroxymethylation on birth outcomes after prenatal per- and polyfluoroalkyl substances (PFAS) exposure in the Michigan mother–infant Pairs cohort

BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) are chemicals that are resistant to degradation and ubiquitous in our environments. PFAS may impact the developing epigenome, but current human evidence is limited to assessments of total DNA methylation. We assessed associations between first t...

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Detalles Bibliográficos
Autores principales: Petroff, Rebekah L., Cavalcante, Raymond G., Langen, Elizabeth S., Dolinoy, Dana C., Padmanabhan, Vasantha, Goodrich, Jaclyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037903/
https://www.ncbi.nlm.nih.gov/pubmed/36964604
http://dx.doi.org/10.1186/s13148-023-01461-5

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