Persistent SARS-CoV-2–specific immune defects in kidney transplant recipients following third mRNA vaccine dose

Kidney transplant recipients (KTRs) show poorer response to SARS-CoV-2 mRNA vaccination, yet response patterns and mechanistic drivers following third doses are ill-defined. We administered third monovalent mRNA vaccines to n = 81 KTRs with negative or low-titer anti-receptor binding domain (RBD) an...

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Detalles Bibliográficos
Autores principales: Werbel, William A., Karaba, Andrew H., Chiang, Teresa Po-Yu, Massie, Allan B., Brown, Diane M., Watson, Natasha, Chahoud, Maggie, Thompson, Elizabeth A., Johnson, Aileen C., Avery, Robin K., Cochran, Willa V., Warren, Daniel, Liang, Tao, Fribourg, Miguel, Huerta, Christopher, Samaha, Hady, Klein, Sabra L., Bettinotti, Maria P., Clarke, William A., Sitaras, Ioannis, Rouphael, Nadine, Cox, Andrea L., Bailey, Justin R., Pekosz, Andrew, Tobian, Aaron A.R., Durand, Christine M., Bridges, Nancy D., Larsen, Christian P., Heeger, Peter S., Segev, Dorry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. on behalf of American Society of Transplantation & American Society of Transplant Surgeons. 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037915/
https://www.ncbi.nlm.nih.gov/pubmed/36966905
http://dx.doi.org/10.1016/j.ajt.2023.03.014

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