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HIV retesting for pregnant and breastfeeding women across maternal child health services in Nampula, Mozambique

BACKGROUND: Repeat HIV testing during pregnancy and breastfeeding identifies women with incident infections, those living with HIV who have been lost to care, and infants at risk for HIV infection. We report data from repeat testing for women in maternal and child health (MCH) services at 10 health...

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Autores principales: Teasdale, Chloe A., Choy, Michelle, Tsiouris, Fatima, De Gusmao, Eduarda Pimentel, Banqueiro, Etelvino C. P., Couto, Aleny, Tibana, Kwalila, Flowers, Nicole, Urso, Marilena, Vitale, Mirriah, Abrams, Elaine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038279/
https://www.ncbi.nlm.nih.gov/pubmed/36961842
http://dx.doi.org/10.1371/journal.pone.0283558
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author Teasdale, Chloe A.
Choy, Michelle
Tsiouris, Fatima
De Gusmao, Eduarda Pimentel
Banqueiro, Etelvino C. P.
Couto, Aleny
Tibana, Kwalila
Flowers, Nicole
Urso, Marilena
Vitale, Mirriah
Abrams, Elaine J.
author_facet Teasdale, Chloe A.
Choy, Michelle
Tsiouris, Fatima
De Gusmao, Eduarda Pimentel
Banqueiro, Etelvino C. P.
Couto, Aleny
Tibana, Kwalila
Flowers, Nicole
Urso, Marilena
Vitale, Mirriah
Abrams, Elaine J.
author_sort Teasdale, Chloe A.
collection PubMed
description BACKGROUND: Repeat HIV testing during pregnancy and breastfeeding identifies women with incident infections, those living with HIV who have been lost to care, and infants at risk for HIV infection. We report data from repeat testing for women in maternal and child health (MCH) services at 10 health facilities in Mozambique. METHODS: Routinely collected data from health facility registers are reported from April-November 2019. From antenatal care (ANC), we report numbers and proportions of women eligible for retesting; returned for care when retesting eligible; retested; and HIV-positive (HIV+) at retesting. From child welfare clinics (CWC), we report mothers retested; tested HIV-positive; HIV+ mothers linked to ART services; HIV-exposed infants (HEI) tested for HIV with polymerase chain reaction (PCR) tests; HEI testing PCR positive; PCR-positive infants linked to care. RESULTS: In ANC, 28,233 pregnant women tested HIV-negative at first ANC visit, 40.7% had a follow-up visit when retesting eligible, among whom 84.8% were retested and 0.3%(N = 26) tested HIV+. In CWC, 26,503 women were tested; 0.8%(N = 212) tested HIV+ and 74.1%(N = 157) of HIV+ women were linked to care. Among 157 HEI identified in CWC, 68.4%(N = 145) received PCR testing and 19.3%(N = 28) tested positive. CONCLUSION: In ANC, less than half of pregnant women eligible for retesting returned for follow-up visits, and test positivity was low among women retested in ANC and CWC. In CWC, linkage to infant testing was poor and almost 20% of HEI were PCR-positive. Implementing retesting for pregnant and breastfeeding women is challenging due to high numbers of women and low testing yield.
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spelling pubmed-100382792023-03-25 HIV retesting for pregnant and breastfeeding women across maternal child health services in Nampula, Mozambique Teasdale, Chloe A. Choy, Michelle Tsiouris, Fatima De Gusmao, Eduarda Pimentel Banqueiro, Etelvino C. P. Couto, Aleny Tibana, Kwalila Flowers, Nicole Urso, Marilena Vitale, Mirriah Abrams, Elaine J. PLoS One Research Article BACKGROUND: Repeat HIV testing during pregnancy and breastfeeding identifies women with incident infections, those living with HIV who have been lost to care, and infants at risk for HIV infection. We report data from repeat testing for women in maternal and child health (MCH) services at 10 health facilities in Mozambique. METHODS: Routinely collected data from health facility registers are reported from April-November 2019. From antenatal care (ANC), we report numbers and proportions of women eligible for retesting; returned for care when retesting eligible; retested; and HIV-positive (HIV+) at retesting. From child welfare clinics (CWC), we report mothers retested; tested HIV-positive; HIV+ mothers linked to ART services; HIV-exposed infants (HEI) tested for HIV with polymerase chain reaction (PCR) tests; HEI testing PCR positive; PCR-positive infants linked to care. RESULTS: In ANC, 28,233 pregnant women tested HIV-negative at first ANC visit, 40.7% had a follow-up visit when retesting eligible, among whom 84.8% were retested and 0.3%(N = 26) tested HIV+. In CWC, 26,503 women were tested; 0.8%(N = 212) tested HIV+ and 74.1%(N = 157) of HIV+ women were linked to care. Among 157 HEI identified in CWC, 68.4%(N = 145) received PCR testing and 19.3%(N = 28) tested positive. CONCLUSION: In ANC, less than half of pregnant women eligible for retesting returned for follow-up visits, and test positivity was low among women retested in ANC and CWC. In CWC, linkage to infant testing was poor and almost 20% of HEI were PCR-positive. Implementing retesting for pregnant and breastfeeding women is challenging due to high numbers of women and low testing yield. Public Library of Science 2023-03-24 /pmc/articles/PMC10038279/ /pubmed/36961842 http://dx.doi.org/10.1371/journal.pone.0283558 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Teasdale, Chloe A.
Choy, Michelle
Tsiouris, Fatima
De Gusmao, Eduarda Pimentel
Banqueiro, Etelvino C. P.
Couto, Aleny
Tibana, Kwalila
Flowers, Nicole
Urso, Marilena
Vitale, Mirriah
Abrams, Elaine J.
HIV retesting for pregnant and breastfeeding women across maternal child health services in Nampula, Mozambique
title HIV retesting for pregnant and breastfeeding women across maternal child health services in Nampula, Mozambique
title_full HIV retesting for pregnant and breastfeeding women across maternal child health services in Nampula, Mozambique
title_fullStr HIV retesting for pregnant and breastfeeding women across maternal child health services in Nampula, Mozambique
title_full_unstemmed HIV retesting for pregnant and breastfeeding women across maternal child health services in Nampula, Mozambique
title_short HIV retesting for pregnant and breastfeeding women across maternal child health services in Nampula, Mozambique
title_sort hiv retesting for pregnant and breastfeeding women across maternal child health services in nampula, mozambique
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038279/
https://www.ncbi.nlm.nih.gov/pubmed/36961842
http://dx.doi.org/10.1371/journal.pone.0283558
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