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Validation of a Simple Instrument of Fast Application to Track Disability in Leprosy Patients
Objective To evaluate a simple and fast diagnostic instrument to be used by any health professional to track the disability presented by leprosy patients. Method Validation study of a diagnostic test performed in a sample of 156 leprosy patients to track functional disability through the shortened...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Revinter Publicações Ltda.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038715/ https://www.ncbi.nlm.nih.gov/pubmed/36969776 http://dx.doi.org/10.1055/s-0042-1742342 |
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author | Pinho, Adriano Bastos Freitas, Murilo Moraes de Fontes, Cor Jesus Fernandes |
author_facet | Pinho, Adriano Bastos Freitas, Murilo Moraes de Fontes, Cor Jesus Fernandes |
author_sort | Pinho, Adriano Bastos |
collection | PubMed |
description | Objective To evaluate a simple and fast diagnostic instrument to be used by any health professional to track the disability presented by leprosy patients. Method Validation study of a diagnostic test performed in a sample of 156 leprosy patients to track functional disability through the shortened disabilities of arm, shoulder, and hand (QuickDASH) questionnaire . The simplified neurological assessment proposed by the World Health Organization was used as a reference. A receiver operating characteristic (ROC) curve was constructed to determine the cutoff point of QuickDASH that best discriminated patients with functional disability caused by leprosy. Results We identified 86 (55.5%) patients with functional disability by simplified neurological evaluation. The performance of the QuickDASH instrument showed that, at a cut-off point of 30 points, the sensitivity and specificity were 72.1% and 68.1% (accuracy of 70.3%), respectively, to identify functional disability, with a positive predictive value of 73.8%. Conclusion The QuickDASH instrument showed good accuracy to track functional disability in leprosy patients, and it may be useful in clinical practice of primary and general outpatient care, with the goal of identifying patients who need specialized reference for the prevention and treatment of this condition. |
format | Online Article Text |
id | pubmed-10038715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Thieme Revinter Publicações Ltda. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100387152023-03-25 Validation of a Simple Instrument of Fast Application to Track Disability in Leprosy Patients Pinho, Adriano Bastos Freitas, Murilo Moraes de Fontes, Cor Jesus Fernandes Rev Bras Ortop (Sao Paulo) Objective To evaluate a simple and fast diagnostic instrument to be used by any health professional to track the disability presented by leprosy patients. Method Validation study of a diagnostic test performed in a sample of 156 leprosy patients to track functional disability through the shortened disabilities of arm, shoulder, and hand (QuickDASH) questionnaire . The simplified neurological assessment proposed by the World Health Organization was used as a reference. A receiver operating characteristic (ROC) curve was constructed to determine the cutoff point of QuickDASH that best discriminated patients with functional disability caused by leprosy. Results We identified 86 (55.5%) patients with functional disability by simplified neurological evaluation. The performance of the QuickDASH instrument showed that, at a cut-off point of 30 points, the sensitivity and specificity were 72.1% and 68.1% (accuracy of 70.3%), respectively, to identify functional disability, with a positive predictive value of 73.8%. Conclusion The QuickDASH instrument showed good accuracy to track functional disability in leprosy patients, and it may be useful in clinical practice of primary and general outpatient care, with the goal of identifying patients who need specialized reference for the prevention and treatment of this condition. Thieme Revinter Publicações Ltda. 2022-06-27 /pmc/articles/PMC10038715/ /pubmed/36969776 http://dx.doi.org/10.1055/s-0042-1742342 Text en Sociedade Brasileira de Ortopedia e Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Pinho, Adriano Bastos Freitas, Murilo Moraes de Fontes, Cor Jesus Fernandes Validation of a Simple Instrument of Fast Application to Track Disability in Leprosy Patients |
title | Validation of a Simple Instrument of Fast Application to Track Disability in Leprosy Patients |
title_full | Validation of a Simple Instrument of Fast Application to Track Disability in Leprosy Patients |
title_fullStr | Validation of a Simple Instrument of Fast Application to Track Disability in Leprosy Patients |
title_full_unstemmed | Validation of a Simple Instrument of Fast Application to Track Disability in Leprosy Patients |
title_short | Validation of a Simple Instrument of Fast Application to Track Disability in Leprosy Patients |
title_sort | validation of a simple instrument of fast application to track disability in leprosy patients |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038715/ https://www.ncbi.nlm.nih.gov/pubmed/36969776 http://dx.doi.org/10.1055/s-0042-1742342 |
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