Cargando…

Intravenously Administered Human Umbilical Cord-Derived Mesenchymal Stem Cell (HucMSC) Improves Cardiac Performance following Infarction via Immune Modulation

Overactive inflammatory responses contribute to progressive cardiac dysfunction after myocardial infarction (MI). Mesenchymal stem cell (MSC) has generated significant interest as potent immune modulators that can regulate excessive immune responses. We hypothesized that intravenous (iv) administrat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Xiaoting, Liu, Jing, Li, Mimi, Lin, Fang, Zhuang, Rulin, Meng, Qingshu, Ma, Xiaoxue, Xin, Yuanfeng, Gong, Xin, He, Zhiying, Han, Wei, Zhou, Xiaohui, Liu, Zhongmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038737/ https://www.ncbi.nlm.nih.gov/pubmed/36970596 http://dx.doi.org/10.1155/2023/6256115

Ejemplares similares

Intramyocardial injected human umbilical cord-derived mesenchymal stem cells (HucMSCs) contribute to the recovery of cardiac function and the migration of CD4(+) T cells into the infarcted heart via CCL5/CCR5 signaling
por: Liu, Jing, et al.
Publicado: (2022)

Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy
por: Wang, Bingying, et al.
Publicado: (2017)

HucMSC-EVs Facilitate In Vitro Development of Maternally Aged Preantral Follicles and Oocytes
por: Zhang, Ying-Yi, et al.
Publicado: (2023)

hucMSC-derived exosomes protect ovarian reserve and restore ovarian function in cisplatin treated mice
por: Xiao, Yue, et al.
Publicado: (2023)

A New Self-Healing Hydrogel Containing hucMSC-Derived Exosomes Promotes Bone Regeneration
por: Wang, Li, et al.
Publicado: (2020)

hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts
por: Wang, Yifei, et al.
Publicado: (2023)

HucMSC‐exosomes carrying miR‐326 inhibit neddylation to relieve inflammatory bowel disease in mice
por: Wang, Gaoying, et al.
Publicado: (2020)

Neutrophil membrane engineered HucMSC sEVs alleviate cisplatin-induced AKI by enhancing cellular uptake and targeting
por: Wu, Peipei, et al.
Publicado: (2022)

Comparison of effects of HucMSCs, exosomes, and conditioned medium on NASH
por: Liang, Chenchen, et al.
Publicado: (2023)

Infusion of Trx-1-Overexpressing hucMSC Prolongs the Survival of Acutely Irradiated NOD/SCID Mice by Decreasing Excessive Inflammatory Injury
por: Hu, JiangWei, et al.
Publicado: (2013)

Galectin-3 Derived from HucMSC Exosomes Promoted Myocardial Fibroblast-to-Myofibroblast Differentiation Associated with β-catenin Upregulation
por: Guo, Qinyu, et al.
Publicado: (2021)

HucMSC-Exo Promote Mucosal Healing in Experimental Colitis by Accelerating Intestinal Stem Cells and Epithelium Regeneration via Wnt Signaling Pathway
por: Liang, Xiaonan, et al.
Publicado: (2023)

Exosomes derived from hucMSC attenuate renal fibrosis through CK1δ/β-TRCP-mediated YAP degradation
por: Ji, Cheng, et al.
Publicado: (2020)

hucMSC-sEVs-Derived 14-3-3ζ Serves as a Bridge between YAP and Autophagy in Diabetic Kidney Disease
por: Yin, Siqi, et al.
Publicado: (2022)

HucMSC-derived exosomes delivered BECN1 induces ferroptosis of hepatic stellate cells via regulating the xCT/GPX4 axis
por: Tan, Youwen, et al.
Publicado: (2022)

HucMSC exosome-delivered 14-3-3ζ alleviates ultraviolet radiation-induced photodamage via SIRT1 pathway modulation
por: Wu, Peipei, et al.
Publicado: (2021)

hucMSC-derived exosomes attenuate colitis by regulating macrophage pyroptosis via the miR-378a-5p/NLRP3 axis
por: Cai, Xiu, et al.
Publicado: (2021)

MiR-146a-5p delivered by hucMSC extracellular vesicles modulates the inflammatory response to sulfur mustard-induced acute lung injury
por: Pei, Zhipeng, et al.
Publicado: (2023)

hucMSC Conditioned Medium Ameliorate Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Oxidative Stress and Inflammation via Nrf2/NF-κB Signaling Pathway
por: Tang, Yue, et al.
Publicado: (2021)

Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants
por: Wang, Yu, et al.
Publicado: (2020)

Exosomes derived from human umbilical cord mesenchymal stem cells reduce tendon injuries via the miR-27b-3p/ARHGAP5/RhoA signaling pathway: Influences of hucMSC-exosomes in tendon injuries
por: Han, Qinghui, et al.
Publicado: (2022)

Preclinical Evaluation of a Single Intravenous Infusion of hUC-MSC (BX-U001) in Rheumatoid Arthritis
por: Liu, Linan, et al.
Publicado: (2020)

HucMSC exosomes promoted imatinib-induced apoptosis in K562-R cells via a miR-145a-5p/USP6/GLS1 axis
por: Chen, Xiaowen, et al.
Publicado: (2022)

Effects of hypoxia-preconditioned HucMSCs on neovascularization and follicle survival in frozen/thawed human ovarian cortex transplanted to immunodeficient mice
por: Cheng, Jiaojiao, et al.
Publicado: (2022)

hucMSCs treatment prevents pulmonary fibrosis by reducing circANKRD42-YAP1-mediated mechanical stiffness
por: Zhang, Haitong, et al.
Publicado: (2023)

MiR-148a-3p within HucMSC-Derived Extracellular Vesicles Suppresses Hsp90b1 to Prevent Fibroblast Collagen Synthesis and Secretion in Silica-Induced Pulmonary Fibrosis
por: Jiang, Qiyue, et al.
Publicado: (2023)

Huc-MSC-derived exosomes modified with the targeting peptide of aHSCs for liver fibrosis therapy
por: Lin, Yan, et al.
Publicado: (2022)

hucMSCs Attenuate IBD through Releasing miR148b-5p to Inhibit the Expression of 15-lox-1 in Macrophages
por: Kang, Jingjing, et al.
Publicado: (2019)

Ultrashort Wave Combined with Human Umbilical Cord Mesenchymal Stem Cell (HUC-MSC) Transplantation Inhibits NLRP3 Inflammasome and Improves Spinal Cord Injury via MK2/TTP Signalling Pathway
por: Na, Li, et al.
Publicado: (2020)

Human umbilical cord mesenchymal stem cells (hUC-MSCs) alleviate paclitaxel-induced spermatogenesis defects and maintain male fertility
por: Zhang, YuSheng, et al.
Publicado: (2023)

hUC-MSC transplantation therapy effects on lupus-prone MRL/lpr mice at early disease stages
por: Guo, Fengbiao, et al.
Publicado: (2023)

Human Umbilical Cord Mesenchymal Stem Cells to Treat Neuromyelitis Optica Spectrum Disorder (hUC–MSC–NMOSD): A Study Protocol for a Prospective, Multicenter, Randomized, Placebo-Controlled Clinical Trial
por: Yao, Xiao-Ying, et al.
Publicado: (2022)

Direct administration of mesenchymal stem cell‐derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence
por: Liang, Xiaoting, et al.
Publicado: (2022)

A novel small molecule compound VCP979 improves ventricular remodeling in murine models of myocardial ischemia/reperfusion injury
por: Liu, Jing, et al.
Publicado: (2020)

Alterations of long noncoding RNAs and mRNAs in extracellular vesicles derived from the murine heart post‐ischemia–reperfusion injury
por: Ge, Xinyu, et al.
Publicado: (2022)

CD4(+)FoxP3(+)CD73(+) regulatory T cell promotes cardiac healing post-myocardial infarction
por: Zhuang, Rulin, et al.
Publicado: (2022)

Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis
por: Liang, Xiaoting, et al.
Publicado: (2021)

hUC-MSC-mediated recovery of subacute spinal cord injury through enhancing the pivotal subunits β3 and γ2 of the GABA(A) receptor
por: Cao, Tingting, et al.
Publicado: (2022)

Human umbilical cord mesenchymal stromal cells promote the regeneration of severe endometrial damage in a rat model: hUCMSCs promote the recovery of severe endometrial damage
por: Zhuang, Mei, et al.
Publicado: (2021)

Fasudil preserves lung endothelial function and reduces pulmonary vascular remodeling in a rat model of end-stage pulmonary hypertension with left heart disease
por: Zhuang, Rulin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_le1eg1qgfver3a4tku5d7h0ciu