Vascular Normalization Was Associated with Colorectal Tumor Regression upon Anti-PD-L1 Combinational Therapy

Anti-PD-L1 therapy exhibits durable efficacy, but only in a small fraction of cancer patients. The immunosuppressive tumor microenvironment (TME) is a crucial obstacle that impedes cancer immunotherapy. Here, we found that anti-PD-L1 therapy coupled with CD4(+) T cell depletion induced colorectal tu...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Gao, Jiayan, He, Yan, Qi, Ziwei, Qian, Long, Chen, Wanpei, Xu, Haiyan, Yue, Yanhua, Mao, Xunyuan, Guo, Shuxin, Zhou, Yan, Zhou, Shuru, Qin, Songbing, Zhang, Xueguang, Huang, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038742/
https://www.ncbi.nlm.nih.gov/pubmed/36969495
http://dx.doi.org/10.1155/2023/5867047

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