BMAL1 collaborates with CLOCK to directly promote DNA double-strand break repair and tumor chemoresistance

Accumulating evidence indicates a correlation between circadian dysfunction and genomic instability. However, whether the circadian machinery directly regulates DNA damage repair, especially in double-strand breaks (DSBs), remains poorly understood. Here, we report that in response to DSBs, BMAL1 is...

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Detalles Bibliográficos
Autores principales: Zhang, Canfeng, Chen, Liping, Sun, Lu, Jin, Heping, Ren, Kai, Liu, Shiqi, Qian, Yongyu, Li, Shupeng, Li, Fangping, Zhu, Chengming, Zhao, Yong, Liu, Haiying, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038804/
https://www.ncbi.nlm.nih.gov/pubmed/36725890
http://dx.doi.org/10.1038/s41388-023-02603-y

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