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New insights into the neuroprotective and beta-secretase1 inhibitor profiles of tirandamycin B isolated from a newly found Streptomyces composti sp. nov.

Tirandamycin (TAM B) is a tetramic acid antibiotic discovered to be active on a screen designed to find compounds with neuroprotective activity. The producing strain, SBST2-5(T), is an actinobacterium that was isolated from wastewater treatment bio–sludge compost collected from Suphanburi province,...

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Detalles Bibliográficos
Autores principales:	Duangupama, Thitikorn, Pratuangdejkul, Jaturong, Chongruchiroj, Sumet, Pittayakhajonwut, Pattama, Intaraudom, Chakapong, Tadtong, Sarin, Nunthanavanit, Patcharawee, Samee, Weerasak, He, Ya-Wen, Tanasupawat, Somboon, Thawai, Chitti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038987/ https://www.ncbi.nlm.nih.gov/pubmed/36964207 http://dx.doi.org/10.1038/s41598-023-32043-3

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