Rabbit derived VL single-domains as promising scaffolds to generate antibody–drug conjugates

Antibody–drug conjugates (ADCs) are among the fastest-growing classes of therapeutics in oncology. Although ADCs are in the spotlight, they still present significant engineering challenges. Therefore, there is an urgent need to develop more stable and effective ADCs. Most rabbit light chains have an...

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Detalles Bibliográficos
Autores principales: André, Ana S., Dias, Joana N. R., Aguiar, Sandra, Nogueira, Sara, Bule, Pedro, Carvalho, Joana Inês, António, João P. M., Cavaco, Marco, Neves, Vera, Oliveira, Soraia, Vicente, Gonçalo, Carrapiço, Belmira, Braz, Berta São, Rütgen, Barbara, Gano, Lurdes, Correia, João D. G., Castanho, Miguel, Goncalves, Joao, Gois, Pedro M. P., Gil, Solange, Tavares, Luís, Aires-da-Silva, Frederico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038998/
https://www.ncbi.nlm.nih.gov/pubmed/36964198
http://dx.doi.org/10.1038/s41598-023-31568-x

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