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Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types

Functional properties caused by TP53 mutations are involved in cancer development and progression. Although most of the mutations lose normal p53 functions, some of them, gain-of-function (GOF) mutations, exhibiting novel oncogenic functions. No reports have analyzed the impact of TP53 mutations on...

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Detalles Bibliográficos
Autores principales: Sasaki, Keiju, Takahashi, Shin, Ouchi, Kota, Otsuki, Yasufumi, Wakayama, Shonosuke, Ishioka, Chikashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039000/
https://www.ncbi.nlm.nih.gov/pubmed/36964217
http://dx.doi.org/10.1038/s41598-023-32092-8

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