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Distribution and association of interpregnancy weight change with subsequent pregnancy outcomes in Asian women

The extent of interpregnancy weight change and its association with subsequent pregnancy outcomes among Asians remain unclear. We examined changes in maternal body mass index (BMI) between the first two deliveries and outcomes in the second delivery. Medical records of women with their first two con...

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Autores principales: Ku, Chee Wai, Cheng, Tuck Seng, Ku, Chee Onn, Zhou, Kathy Xinzhuo, Cheung, Yin Bun, Godfrey, Keith M., Han, Wee Meng, Yap, Fabian, Chan, Jerry Kok Yen, Loy, See Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039003/
https://www.ncbi.nlm.nih.gov/pubmed/36964283
http://dx.doi.org/10.1038/s41598-023-31954-5
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author Ku, Chee Wai
Cheng, Tuck Seng
Ku, Chee Onn
Zhou, Kathy Xinzhuo
Cheung, Yin Bun
Godfrey, Keith M.
Han, Wee Meng
Yap, Fabian
Chan, Jerry Kok Yen
Loy, See Ling
author_facet Ku, Chee Wai
Cheng, Tuck Seng
Ku, Chee Onn
Zhou, Kathy Xinzhuo
Cheung, Yin Bun
Godfrey, Keith M.
Han, Wee Meng
Yap, Fabian
Chan, Jerry Kok Yen
Loy, See Ling
author_sort Ku, Chee Wai
collection PubMed
description The extent of interpregnancy weight change and its association with subsequent pregnancy outcomes among Asians remain unclear. We examined changes in maternal body mass index (BMI) between the first two deliveries and outcomes in the second delivery. Medical records of women with their first two consecutive deliveries between 2015 and 2020 at KK Women’s and Children’s Hospital, Singapore were retrieved. Gestational-age-adjusted BMI was determined by standardising to 12 weeks gestation and interpregnancy BMI change was calculated as the difference between both pregnancies. Pregnancy outcomes were analysed using modified Poisson regression models. Of 6264 included women with a median interpregnancy interval of 1.44 years, 40.7% had a stable BMI change within ± 1 kg/m(2), 10.3% lost > 1 kg/m(2), 34.3% gained 1–3 kg/m(2) and 14.8% gained ≥ 3 kg/m(2). Compared to women with stable BMI change, those with > 1 kg/m(2) loss had higher risk of low birthweight (adjusted risk ratio [RR] 1.36; 95% confidence interval 1.02–1.80), while those with 1–3 kg/m(2) gain had higher risks of large-for-gestational-age birth (1.16; 1.03–1.31), gestational diabetes (1.25; 1.06–1.49) and emergency Caesarean delivery (1.16; 1.03–1.31); these risks were higher in those with ≥ 3 kg/m(2) gain. Our study strengthens the case for interpregnancy weight management to improve subsequent pregnancy outcomes.
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spelling pubmed-100390032023-03-26 Distribution and association of interpregnancy weight change with subsequent pregnancy outcomes in Asian women Ku, Chee Wai Cheng, Tuck Seng Ku, Chee Onn Zhou, Kathy Xinzhuo Cheung, Yin Bun Godfrey, Keith M. Han, Wee Meng Yap, Fabian Chan, Jerry Kok Yen Loy, See Ling Sci Rep Article The extent of interpregnancy weight change and its association with subsequent pregnancy outcomes among Asians remain unclear. We examined changes in maternal body mass index (BMI) between the first two deliveries and outcomes in the second delivery. Medical records of women with their first two consecutive deliveries between 2015 and 2020 at KK Women’s and Children’s Hospital, Singapore were retrieved. Gestational-age-adjusted BMI was determined by standardising to 12 weeks gestation and interpregnancy BMI change was calculated as the difference between both pregnancies. Pregnancy outcomes were analysed using modified Poisson regression models. Of 6264 included women with a median interpregnancy interval of 1.44 years, 40.7% had a stable BMI change within ± 1 kg/m(2), 10.3% lost > 1 kg/m(2), 34.3% gained 1–3 kg/m(2) and 14.8% gained ≥ 3 kg/m(2). Compared to women with stable BMI change, those with > 1 kg/m(2) loss had higher risk of low birthweight (adjusted risk ratio [RR] 1.36; 95% confidence interval 1.02–1.80), while those with 1–3 kg/m(2) gain had higher risks of large-for-gestational-age birth (1.16; 1.03–1.31), gestational diabetes (1.25; 1.06–1.49) and emergency Caesarean delivery (1.16; 1.03–1.31); these risks were higher in those with ≥ 3 kg/m(2) gain. Our study strengthens the case for interpregnancy weight management to improve subsequent pregnancy outcomes. Nature Publishing Group UK 2023-03-24 /pmc/articles/PMC10039003/ /pubmed/36964283 http://dx.doi.org/10.1038/s41598-023-31954-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ku, Chee Wai
Cheng, Tuck Seng
Ku, Chee Onn
Zhou, Kathy Xinzhuo
Cheung, Yin Bun
Godfrey, Keith M.
Han, Wee Meng
Yap, Fabian
Chan, Jerry Kok Yen
Loy, See Ling
Distribution and association of interpregnancy weight change with subsequent pregnancy outcomes in Asian women
title Distribution and association of interpregnancy weight change with subsequent pregnancy outcomes in Asian women
title_full Distribution and association of interpregnancy weight change with subsequent pregnancy outcomes in Asian women
title_fullStr Distribution and association of interpregnancy weight change with subsequent pregnancy outcomes in Asian women
title_full_unstemmed Distribution and association of interpregnancy weight change with subsequent pregnancy outcomes in Asian women
title_short Distribution and association of interpregnancy weight change with subsequent pregnancy outcomes in Asian women
title_sort distribution and association of interpregnancy weight change with subsequent pregnancy outcomes in asian women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039003/
https://www.ncbi.nlm.nih.gov/pubmed/36964283
http://dx.doi.org/10.1038/s41598-023-31954-5
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