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Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration

There is emerging evidence about the predictive role of homologous recombination deficiency (HRD), but this is less defined in gastrointestinal (GI) and thoracic malignancies. We reviewed whole genome (WGS) and transcriptomic (RNA-Seq) data from advanced GI and thoracic cancers in the Personalized O...

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Detalles Bibliográficos
Autores principales:	Tsang, Erica S., Csizmok, Veronika, Williamson, Laura M., Pleasance, Erin, Topham, James T., Karasinska, Joanna M., Titmuss, Emma, Schrader, Intan, Yip, Stephen, Tessier-Cloutier, Basile, Mungall, Karen, Ng, Tony, Sun, Sophie, Lim, Howard J., Loree, Jonathan M., Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039042/ https://www.ncbi.nlm.nih.gov/pubmed/36964191 http://dx.doi.org/10.1038/s41698-023-00368-x

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