Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients

While type I interferon (IFN) is best known for its key role against viral infection, accumulating preclinical and clinical data indicate that robust type I IFN production in the tumor microenvironment promotes cancer immunosurveillance and contributes to the efficacy of various antineoplastic agent...

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Detalles Bibliográficos
Autores principales: Holicek, Peter, Truxova, Iva, Rakova, Jana, Salek, Cyril, Hensler, Michal, Kovar, Marek, Reinis, Milan, Mikyskova, Romana, Pasulka, Josef, Vosahlikova, Sarka, Remesova, Hana, Valentova, Iva, Lysak, Daniel, Holubova, Monika, Kaspar, Petr, Prochazka, Jan, Kasikova, Lenka, Spisek, Radek, Galluzzi, Lorenzo, Fucikova, Jitka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039058/
https://www.ncbi.nlm.nih.gov/pubmed/36964168
http://dx.doi.org/10.1038/s41419-023-05728-w

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