Direct reprogramming of human fibroblasts into insulin-producing cells using transcription factors

Direct lineage reprogramming of one somatic cell into another without transitioning through a progenitor stage has emerged as a strategy to generate clinically relevant cell types. One cell type of interest is the pancreatic insulin-producing β cell whose loss and/or dysfunction leads to diabetes. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Fontcuberta-PiSunyer, Marta, García-Alamán, Ainhoa, Prades, Èlia, Téllez, Noèlia, Alves-Figueiredo, Hugo, Ramos-Rodríguez, Mireia, Enrich, Carlos, Fernandez-Ruiz, Rebeca, Cervantes, Sara, Clua, Laura, Ramón-Azcón, Javier, Broca, Christophe, Wojtusciszyn, Anne, Montserrat, Nuria, Pasquali, Lorenzo, Novials, Anna, Servitja, Joan-Marc, Vidal, Josep, Gomis, Ramon, Gasa, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039074/
https://www.ncbi.nlm.nih.gov/pubmed/36964318
http://dx.doi.org/10.1038/s42003-023-04627-2

Ejemplares similares

Ejemplares similares