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The Caribbean-Hispanic Alzheimer’s disease brain transcriptome reveals ancestry-specific disease mechanisms

Identifying ancestry-specific molecular profiles of late-onset Alzheimer’s Disease (LOAD) in brain tissue is crucial to understand novel mechanisms and develop effective interventions in non-European, high-risk populations. We performed gene differential expression (DE) and consensus network-based a...

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Detalles Bibliográficos
Autores principales: Felsky, Daniel, Santa-Maria, Ismael, Cosacak, Mehmet Ilyas, French, Leon, Schneider, Julie A., Bennett, David A., De Jager, Philip L., Kizil, Caghan, Tosto, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039465/
https://www.ncbi.nlm.nih.gov/pubmed/36462719
http://dx.doi.org/10.1016/j.nbd.2022.105938