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Association of OPRM1, MIR23B, and MIR107 Genetic Variability with Acute Pain, Chronic Pain and Adverse Effects after Postoperative Tramadol and Paracetamol Treatment in Breast Cancer

BACKGROUND: Tramadol is an opioid analgesic often used for pain management after breast cancer surgery. Its analgesic activity is due to the activation of the μ-opioid receptor, encoded by the OPRM1 gene. This study investigated the association of genetic variability in OPRM1 and its regulatory miRN...

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Detalles Bibliográficos
Autores principales:	Vidic, Zala, Goricar, Katja, Strazisar, Branka, Besic, Nikola, Dolzan, Vita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sciendo 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039478/ https://www.ncbi.nlm.nih.gov/pubmed/36942908 http://dx.doi.org/10.2478/raon-2023-0003

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