Unleashing the potential of combining FGFR inhibitor and immune checkpoint blockade for FGF/FGFR signaling in tumor microenvironment

BACKGROUND: Fibroblast growth factors (FGFs) and their receptors (FGFRs) play a crucial role in cell fate and angiogenesis, with dysregulation of the signaling axis driving tumorigenesis. Therefore, many studies have targeted FGF/FGFR signaling for cancer therapy and several FGFR inhibitors have pro...

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Detalles Bibliográficos
Autores principales: Ruan, Ruiwen, Li, Li, Li, Xuan, Huang, Chunye, Zhang, Zhanmin, Zhong, Hongguang, Zeng, Shaocheng, Shi, Qianqian, Xia, Yang, Zeng, Qinru, Wen, Qin, Chen, Jingyi, Dai, Xiaofeng, Xiong, Jianping, Xiang, Xiaojun, Lei, Wan, Deng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039534/
https://www.ncbi.nlm.nih.gov/pubmed/36966334
http://dx.doi.org/10.1186/s12943-023-01761-7

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