Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia

High hyperdiploid acute lymphoblastic leukemia (HeH ALL), one of the most common childhood malignancies, is driven by nonrandom aneuploidy (abnormal chromosome numbers) mainly comprising chromosomal gains. In this study, we investigate how aneuploidy in HeH ALL arises. Single cell whole genome seque...

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Detalles Bibliográficos
Autores principales: Woodward, Eleanor L., Yang, Minjun, Moura-Castro, Larissa H., van den Bos, Hilda, Gunnarsson, Rebeqa, Olsson-Arvidsson, Linda, Spierings, Diana C. J., Castor, Anders, Duployez, Nicolas, Zaliova, Marketa, Zuna, Jan, Johansson, Bertil, Foijer, Floris, Paulsson, Kajsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039905/
https://www.ncbi.nlm.nih.gov/pubmed/36966135
http://dx.doi.org/10.1038/s41467-023-37356-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039905/
https://www.ncbi.nlm.nih.gov/pubmed/36966135
http://dx.doi.org/10.1038/s41467-023-37356-5

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