iPAPP: study protocol for a multicentre randomised controlled trial comparing safety and efficacy of intravenous paracetamol and indomethacin for the treatment of patent ductus arteriosus in preterm infants

INTRODUCTION: Patent ductus arteriosus (PDA) causes severe morbidity in premature infants. Although the use of indomethacin is the standard therapy for PDA, it is sometimes not applicable because of its adverse effects, such as renal and platelet dysfunctions. Paracetamol has emerged as an alternati...

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Detalles Bibliográficos
Autores principales: Namba, Fumihiko, Honda, Masakazu, Sakatani, Shun, Motojima, Yukiko, Kikuchi, Kayoko, Sako, Mayumi, Ogawa, Kunio, Mikami, Masashi, Kawada, Kou, Fukuoka, Noriyasu, Ueda, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Paediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039996/
https://www.ncbi.nlm.nih.gov/pubmed/36958775
http://dx.doi.org/10.1136/bmjopen-2022-069314

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