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Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure

BACKGROUND: Chronic heart failure (CHF) is regarded as common clinical heart disease. This study aims to investigate the clinical diagnostic value of echocardiography (Echo) and serum C-reactive protein (CRP) levels in patients with CHF. METHODS: A total of 75 patients with CHF (42 males, 33 females...

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Autor principal: Zhang, Yongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040132/
https://www.ncbi.nlm.nih.gov/pubmed/36966338
http://dx.doi.org/10.1186/s13019-023-02176-7
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author Zhang, Yongxia
author_facet Zhang, Yongxia
author_sort Zhang, Yongxia
collection PubMed
description BACKGROUND: Chronic heart failure (CHF) is regarded as common clinical heart disease. This study aims to investigate the clinical diagnostic value of echocardiography (Echo) and serum C-reactive protein (CRP) levels in patients with CHF. METHODS: A total of 75 patients with CHF (42 males, 33 females, age 62.72 ± 1.06 years) were enrolled as study subjects, with 70 non-CHF subjects (38 males, 32 females, age 62.44 ± 1.28 years) as controls. The left ventricular ejection fraction (LVEF), fraction shortening rate of the left ventricle (FS), and early to late diastolic filling (E/A) were determined by Echo, followed by an examination of the expression of serum CRP by ELISA. In addition, the Pearson method was used to analyze the correlation between echocardiographic quantitative parameters (EQPs) (LVEF, FS, and E/A) and serum CRP levels. Receiver operating characteristic (ROC) curve was adopted to evaluate the diagnostic efficacy of EQPs and serum CRP levels for CHF. The independent risk factors for CHF patients were measured by logistics regression analysis. RESULTS: The serum CRP level of CHF patients was elevated, the values of LVEF and FS decreased, and the E/A values increased. ROC curve revealed that the EQPs (LVEF, FS, and E/A) combined with serum CRP had high diagnostic values for CHF patients. Logistic regression analysis showed that the EQPs (LVEF, FS, and E/A) and serum CRP levels were independent risk factors for CHF patients. CONCLUSION: Echo combined with serum CRP level has high clinical diagnostic values for CHF patients.
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spelling pubmed-100401322023-03-27 Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure Zhang, Yongxia J Cardiothorac Surg Research BACKGROUND: Chronic heart failure (CHF) is regarded as common clinical heart disease. This study aims to investigate the clinical diagnostic value of echocardiography (Echo) and serum C-reactive protein (CRP) levels in patients with CHF. METHODS: A total of 75 patients with CHF (42 males, 33 females, age 62.72 ± 1.06 years) were enrolled as study subjects, with 70 non-CHF subjects (38 males, 32 females, age 62.44 ± 1.28 years) as controls. The left ventricular ejection fraction (LVEF), fraction shortening rate of the left ventricle (FS), and early to late diastolic filling (E/A) were determined by Echo, followed by an examination of the expression of serum CRP by ELISA. In addition, the Pearson method was used to analyze the correlation between echocardiographic quantitative parameters (EQPs) (LVEF, FS, and E/A) and serum CRP levels. Receiver operating characteristic (ROC) curve was adopted to evaluate the diagnostic efficacy of EQPs and serum CRP levels for CHF. The independent risk factors for CHF patients were measured by logistics regression analysis. RESULTS: The serum CRP level of CHF patients was elevated, the values of LVEF and FS decreased, and the E/A values increased. ROC curve revealed that the EQPs (LVEF, FS, and E/A) combined with serum CRP had high diagnostic values for CHF patients. Logistic regression analysis showed that the EQPs (LVEF, FS, and E/A) and serum CRP levels were independent risk factors for CHF patients. CONCLUSION: Echo combined with serum CRP level has high clinical diagnostic values for CHF patients. BioMed Central 2023-03-25 /pmc/articles/PMC10040132/ /pubmed/36966338 http://dx.doi.org/10.1186/s13019-023-02176-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zhang, Yongxia
Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure
title Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure
title_full Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure
title_fullStr Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure
title_full_unstemmed Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure
title_short Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure
title_sort diagnostic value of echocardiography combined with serum c-reactive protein level in chronic heart failure
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040132/
https://www.ncbi.nlm.nih.gov/pubmed/36966338
http://dx.doi.org/10.1186/s13019-023-02176-7
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