Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination

Multiple sclerosis (MS) is an inflammatory-mediated demyelinating disease of the central nervous system (CNS). Although studies have demonstrated that microglia facilitate remyelination in demyelinating diseases, the underlying mechanisms are still not fully characterized. We found that aryl hydroca...

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Detalles Bibliográficos
Autores principales: Wang, Yumeng, Sun, Jingxian, Zhu, Keying, Wang, Danjie, Zhao, Xiaoqiang, Zhang, Hongyu, Wu, Shuai, Wang, Yanqing, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040134/
https://www.ncbi.nlm.nih.gov/pubmed/36966295
http://dx.doi.org/10.1186/s12974-023-02764-3

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