CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst

BACKGROUND: Fatty acid metabolism in the hypothalamus has an important role in food intake, but its specific role in AgRP neurons is poorly understood. Here, we examined whether carnitinea palmitoyltransferase 1A (CPT1A), a key enzyme in mitochondrial fatty acid oxidation, affects energy balance. ME...

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Detalles Bibliográficos
Autores principales: Zagmutt, Sebastián, Mera, Paula, González-García, Ismael, Ibeas, Kevin, Romero, María del Mar, Obri, Arnaud, Martin, Beatriz, Esteve-Codina, Anna, Soler-Vázquez, M. Carmen, Bastias-Pérez, Marianela, Cañes, Laia, Augé, Elisabeth, Pelegri, Carme, Vilaplana, Jordi, Ariza, Xavier, García, Jordi, Martinez-González, José, Casals, Núria, López, Miguel, Palmiter, Richard, Sanz, Elisenda, Quintana, Albert, Herrero, Laura, Serra, Dolors
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040140/
https://www.ncbi.nlm.nih.gov/pubmed/36966335
http://dx.doi.org/10.1186/s13293-023-00498-8

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