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Impaired episodic-like memory in a mouse model of Alzheimer's disease is associated with hyperactivity in prefrontal–hippocampal regions
Alzheimer's disease (AD) is a degenerative brain disorder with a long prodromal period. An APP(NL-G-F) knock-in mouse model is a preclinical model to study incipient pathologies during the early stages of AD. Despite behavioral tests revealing broad cognitive deficits in APP(NL-G-F) mice, detec...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040242/ https://www.ncbi.nlm.nih.gov/pubmed/36897115 http://dx.doi.org/10.1242/dmm.049945 |