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Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis

Accumulation of senescent cells contributes to age-related diseases including idiopathic pulmonary fibrosis (IPF). Insulin-like growth factor binding proteins (IGFBPs) regulate many biological processes; however, the functional contributions of IGFBP2 in lung fibrosis remain largely unclear. Here, w...

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Detalles Bibliográficos
Autores principales:	Chin, Chiahsuan, Ravichandran, Ranjithkumar, Sanborn, Kristina, Fleming, Timothy, Wheatcroft, Stephen B., Kearney, Mark T., Tokman, Sofya, Walia, Rajat, Smith, Michael A., Flint, David J., Mohanakumar, Thalachallour, Bremner, Ross M., Sureshbabu, Angara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040381/ https://www.ncbi.nlm.nih.gov/pubmed/36787736 http://dx.doi.org/10.1016/j.xcrm.2023.100945

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