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A vigorous study of fractional order mathematical model for SARS-CoV-2 epidemic with Mittag-Leffler kernel
SARS-CoV-2 and its variants have been investigated using a variety of mathematical models. In contrast to multi-strain models, SARS-CoV-2 models exhibit a memory effect that is often overlooked and more realistic. Atangana-Baleanu’s fractional-order operator is discussed in this manuscript for the a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040393/ http://dx.doi.org/10.1016/j.aej.2023.03.037 |
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author | Chu, Yu-Ming Zarin, Rahat Khan, Asad Murtaza, Saqib |
author_facet | Chu, Yu-Ming Zarin, Rahat Khan, Asad Murtaza, Saqib |
author_sort | Chu, Yu-Ming |
collection | PubMed |
description | SARS-CoV-2 and its variants have been investigated using a variety of mathematical models. In contrast to multi-strain models, SARS-CoV-2 models exhibit a memory effect that is often overlooked and more realistic. Atangana-Baleanu’s fractional-order operator is discussed in this manuscript for the analysis of the transmission dynamics of SARS-CoV-2. We investigated the transmission mechanism of the SARS-CoV-2 virus using the non-local Atangana-Baleanu fractional-order approach taking into account the different phases of infection and transmission routes. Using conventional ordinary derivative operators, our first step will be to develop a model for the proposed study. As part of the extension, we will incorporate fractional order derivatives into the model where the used operator is the fractional order operator of order [Formula: see text]. Additionally, some basic aspects of the proposed model are examined in addition to calculating the reproduction number and determining the possible equilibrium. Stability analysis of the model is conducted to determine the necessary equilibrium conditions as they are also required in developing a numerical setup. Utilizing the theory of nonlinear functional analysis, for the model, Ulam-Hyers’ stability is established. We present a numerical scheme based on Newton’s polynomial in order to set up an iterative algorithm for the proposed ABC system. The application of this scheme to a variety of values of [Formula: see text] indicates that there is a relationship between infection dynamics and the derivative’s order. We present further simulations which demonstrate the importance and cruciality of different parameters, as well as their effect on the dynamics and administer the disease. Furthermore, this study will provide a better understanding of the mechanisms underlying contagious diseases, thus supporting the development of policies to control them. |
format | Online Article Text |
id | pubmed-10040393 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100403932023-03-27 A vigorous study of fractional order mathematical model for SARS-CoV-2 epidemic with Mittag-Leffler kernel Chu, Yu-Ming Zarin, Rahat Khan, Asad Murtaza, Saqib Alexandria Engineering Journal Original Article SARS-CoV-2 and its variants have been investigated using a variety of mathematical models. In contrast to multi-strain models, SARS-CoV-2 models exhibit a memory effect that is often overlooked and more realistic. Atangana-Baleanu’s fractional-order operator is discussed in this manuscript for the analysis of the transmission dynamics of SARS-CoV-2. We investigated the transmission mechanism of the SARS-CoV-2 virus using the non-local Atangana-Baleanu fractional-order approach taking into account the different phases of infection and transmission routes. Using conventional ordinary derivative operators, our first step will be to develop a model for the proposed study. As part of the extension, we will incorporate fractional order derivatives into the model where the used operator is the fractional order operator of order [Formula: see text]. Additionally, some basic aspects of the proposed model are examined in addition to calculating the reproduction number and determining the possible equilibrium. Stability analysis of the model is conducted to determine the necessary equilibrium conditions as they are also required in developing a numerical setup. Utilizing the theory of nonlinear functional analysis, for the model, Ulam-Hyers’ stability is established. We present a numerical scheme based on Newton’s polynomial in order to set up an iterative algorithm for the proposed ABC system. The application of this scheme to a variety of values of [Formula: see text] indicates that there is a relationship between infection dynamics and the derivative’s order. We present further simulations which demonstrate the importance and cruciality of different parameters, as well as their effect on the dynamics and administer the disease. Furthermore, this study will provide a better understanding of the mechanisms underlying contagious diseases, thus supporting the development of policies to control them. THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. 2023-05-15 2023-03-27 /pmc/articles/PMC10040393/ http://dx.doi.org/10.1016/j.aej.2023.03.037 Text en © 2023 THE AUTHORS Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Original Article Chu, Yu-Ming Zarin, Rahat Khan, Asad Murtaza, Saqib A vigorous study of fractional order mathematical model for SARS-CoV-2 epidemic with Mittag-Leffler kernel |
title | A vigorous study of fractional order mathematical model for SARS-CoV-2 epidemic with Mittag-Leffler kernel |
title_full | A vigorous study of fractional order mathematical model for SARS-CoV-2 epidemic with Mittag-Leffler kernel |
title_fullStr | A vigorous study of fractional order mathematical model for SARS-CoV-2 epidemic with Mittag-Leffler kernel |
title_full_unstemmed | A vigorous study of fractional order mathematical model for SARS-CoV-2 epidemic with Mittag-Leffler kernel |
title_short | A vigorous study of fractional order mathematical model for SARS-CoV-2 epidemic with Mittag-Leffler kernel |
title_sort | vigorous study of fractional order mathematical model for sars-cov-2 epidemic with mittag-leffler kernel |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040393/ http://dx.doi.org/10.1016/j.aej.2023.03.037 |
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