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Lecanemab reduces brain amyloid-β and delays cognitive worsening
Lecanemab cleared amyloid-β in two-thirds and reduced the rate of cognitive and functional worsening in people with mild cognitive impairment and mild dementia due to Alzheimer disease in an 18-month double-blinded randomized placebo-controlled trial reported by van Dyck et al.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040446/ https://www.ncbi.nlm.nih.gov/pubmed/36948153 http://dx.doi.org/10.1016/j.xcrm.2023.100982 |
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author | Knopman, David S. |
author_facet | Knopman, David S. |
author_sort | Knopman, David S. |
collection | PubMed |
description | Lecanemab cleared amyloid-β in two-thirds and reduced the rate of cognitive and functional worsening in people with mild cognitive impairment and mild dementia due to Alzheimer disease in an 18-month double-blinded randomized placebo-controlled trial reported by van Dyck et al. |
format | Online Article Text |
id | pubmed-10040446 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-100404462023-03-28 Lecanemab reduces brain amyloid-β and delays cognitive worsening Knopman, David S. Cell Rep Med Spotlight Lecanemab cleared amyloid-β in two-thirds and reduced the rate of cognitive and functional worsening in people with mild cognitive impairment and mild dementia due to Alzheimer disease in an 18-month double-blinded randomized placebo-controlled trial reported by van Dyck et al. Elsevier 2023-03-21 /pmc/articles/PMC10040446/ /pubmed/36948153 http://dx.doi.org/10.1016/j.xcrm.2023.100982 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Spotlight Knopman, David S. Lecanemab reduces brain amyloid-β and delays cognitive worsening |
title | Lecanemab reduces brain amyloid-β and delays cognitive worsening |
title_full | Lecanemab reduces brain amyloid-β and delays cognitive worsening |
title_fullStr | Lecanemab reduces brain amyloid-β and delays cognitive worsening |
title_full_unstemmed | Lecanemab reduces brain amyloid-β and delays cognitive worsening |
title_short | Lecanemab reduces brain amyloid-β and delays cognitive worsening |
title_sort | lecanemab reduces brain amyloid-β and delays cognitive worsening |
topic | Spotlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040446/ https://www.ncbi.nlm.nih.gov/pubmed/36948153 http://dx.doi.org/10.1016/j.xcrm.2023.100982 |
work_keys_str_mv | AT knopmandavids lecanemabreducesbrainamyloidbanddelayscognitiveworsening |