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Increased gestational palmitic acid predisposes offspring to congenital heart disease

Identification of the causes for congenital heart disease (CHD) is a prerequisite for precise prevention and personalized treatment of CHD. Zhao et al.(1) show increased that gestational serum palmitic acid (PA) predisposes offspring to CHD by perturbating the MARS/K-Hcy/GATA4 signaling pathway.

Detalles Bibliográficos
Autores principales: Lv, Yang, Gao, Ri-Feng, Yang, Chen-Xi, Xu, Ying-Jia, Yang, Yi-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040449/
https://www.ncbi.nlm.nih.gov/pubmed/36948150
http://dx.doi.org/10.1016/j.xcrm.2023.100984
Descripción
Sumario:Identification of the causes for congenital heart disease (CHD) is a prerequisite for precise prevention and personalized treatment of CHD. Zhao et al.(1) show increased that gestational serum palmitic acid (PA) predisposes offspring to CHD by perturbating the MARS/K-Hcy/GATA4 signaling pathway.