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Regulated control of virus replication by 4-hydroxytamoxifen-induced splicing

Designing a modified virus that can be controlled to replicate will facilitate the study of pathogenic mechanisms of virus and virus–host interactions. Here, we report a universal switch element that enables precise control of virus replication after exposure to a small molecule. Inteins mediate a t...

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Detalles Bibliográficos
Autores principales: Zhao, Zhenghao, Wang, Busen, Wu, Shipo, Zhang, Zhe, Chen, Yi, Zhang, Jinlong, Wang, Yudong, Zhu, Danni, Li, Yao, Xu, Jinghan, Hou, Lihua, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040539/
https://www.ncbi.nlm.nih.gov/pubmed/36992923
http://dx.doi.org/10.3389/fmicb.2023.1112580