Cargando…

Microbial community structure dynamics of invasive bullfrog with meningitis-like infectious disease

Meningitis-like infectious disease (MID) (also known as frog cataract and torticollis) is a disease prone to occur in amphibians and reptiles. It is highly contagious and has a high mortality rate. In this study, we sampled and sequenced microbiomes from oral and intestinal samples of five normal an...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wengang, Fan, Guangwei, Sun, Ke, Liu, Jingru, Liu, Jinyan, Wang, Yu, Li, En, Wu, Xiaobing, Shen, Liang, Pan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040567/
https://www.ncbi.nlm.nih.gov/pubmed/36992930
http://dx.doi.org/10.3389/fmicb.2023.1126195
_version_ 1784912502271770624
author Li, Wengang
Fan, Guangwei
Sun, Ke
Liu, Jingru
Liu, Jinyan
Wang, Yu
Li, En
Wu, Xiaobing
Shen, Liang
Pan, Tao
author_facet Li, Wengang
Fan, Guangwei
Sun, Ke
Liu, Jingru
Liu, Jinyan
Wang, Yu
Li, En
Wu, Xiaobing
Shen, Liang
Pan, Tao
author_sort Li, Wengang
collection PubMed
description Meningitis-like infectious disease (MID) (also known as frog cataract and torticollis) is a disease prone to occur in amphibians and reptiles. It is highly contagious and has a high mortality rate. In this study, we sampled and sequenced microbiomes from oral and intestinal samples of five normal and five diseased bullfrogs. The analysis found that the richness, uniformity, and abundance of the microbial community of the diseased bullfrogs were significantly higher than those of the normal bullfrogs in both the oral cavity and the gut. In the diseased group, the abundance of Elizabethkingia significantly increased and that of Lactococcus significantly decreased. It showed that the structure of the microbial community had changed a lot in diseased frogs. After the pathogenic bacteria infected the body, it might be make the decline in the immune function of the body declined, and resulting in some conditional pathogenic bacteria in the water body further infecting the body. As a result, the richness and composition of the microbial community significantly changed. This study can provide a theoretical basis for the control of MID of bullfrogs.
format Online
Article
Text
id pubmed-10040567
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-100405672023-03-28 Microbial community structure dynamics of invasive bullfrog with meningitis-like infectious disease Li, Wengang Fan, Guangwei Sun, Ke Liu, Jingru Liu, Jinyan Wang, Yu Li, En Wu, Xiaobing Shen, Liang Pan, Tao Front Microbiol Microbiology Meningitis-like infectious disease (MID) (also known as frog cataract and torticollis) is a disease prone to occur in amphibians and reptiles. It is highly contagious and has a high mortality rate. In this study, we sampled and sequenced microbiomes from oral and intestinal samples of five normal and five diseased bullfrogs. The analysis found that the richness, uniformity, and abundance of the microbial community of the diseased bullfrogs were significantly higher than those of the normal bullfrogs in both the oral cavity and the gut. In the diseased group, the abundance of Elizabethkingia significantly increased and that of Lactococcus significantly decreased. It showed that the structure of the microbial community had changed a lot in diseased frogs. After the pathogenic bacteria infected the body, it might be make the decline in the immune function of the body declined, and resulting in some conditional pathogenic bacteria in the water body further infecting the body. As a result, the richness and composition of the microbial community significantly changed. This study can provide a theoretical basis for the control of MID of bullfrogs. Frontiers Media S.A. 2023-03-13 /pmc/articles/PMC10040567/ /pubmed/36992930 http://dx.doi.org/10.3389/fmicb.2023.1126195 Text en Copyright © 2023 Li, Fan, Sun, Liu, Liu, Wang, Li, Wu, Shen and Pan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Li, Wengang
Fan, Guangwei
Sun, Ke
Liu, Jingru
Liu, Jinyan
Wang, Yu
Li, En
Wu, Xiaobing
Shen, Liang
Pan, Tao
Microbial community structure dynamics of invasive bullfrog with meningitis-like infectious disease
title Microbial community structure dynamics of invasive bullfrog with meningitis-like infectious disease
title_full Microbial community structure dynamics of invasive bullfrog with meningitis-like infectious disease
title_fullStr Microbial community structure dynamics of invasive bullfrog with meningitis-like infectious disease
title_full_unstemmed Microbial community structure dynamics of invasive bullfrog with meningitis-like infectious disease
title_short Microbial community structure dynamics of invasive bullfrog with meningitis-like infectious disease
title_sort microbial community structure dynamics of invasive bullfrog with meningitis-like infectious disease
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040567/
https://www.ncbi.nlm.nih.gov/pubmed/36992930
http://dx.doi.org/10.3389/fmicb.2023.1126195
work_keys_str_mv AT liwengang microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease
AT fanguangwei microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease
AT sunke microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease
AT liujingru microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease
AT liujinyan microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease
AT wangyu microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease
AT lien microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease
AT wuxiaobing microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease
AT shenliang microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease
AT pantao microbialcommunitystructuredynamicsofinvasivebullfrogwithmeningitislikeinfectiousdisease