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Open Thy Lattice Osteoclast, Resorb me!
Osteoclasts degrade bone using Cathepsin K and two metalloproteinases: MMP9 and MMP14. In addition to cleaving collagen, Zhu et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202206121) discover that MMP9 and MMP14 also proteolyze galectin-3 on the cell surface. This process drives a galectin-...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040631/ https://www.ncbi.nlm.nih.gov/pubmed/36928467 http://dx.doi.org/10.1083/jcb.202302033 |