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Genome editing in rice mediated by miniature size Cas nuclease SpCas12f

Cas9 derived from Streptococcus pyogenes (SpCas9) is used widely in genome editing using the CRISPR-Cas system due to its high activity, but is a relatively large molecule (1,368 amino acid (a.a.) residues). Recently, targeted mutagenesis in human cells and maize using Cas12f derived from Syntrophom...

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Detalles Bibliográficos
Autores principales: Sukegawa, Satoru, Nureki, Osamu, Toki, Seiichi, Saika, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040665/
https://www.ncbi.nlm.nih.gov/pubmed/36992681
http://dx.doi.org/10.3389/fgeed.2023.1138843

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