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Deletion of NADPH oxidase 2 attenuates cisplatin-induced acute kidney injury through reducing ROS-induced proximal tubular cell injury and inflammation

BACKGROUNDS: Cisplatin is a commonly used chemotherapeutic agent in cancer treatment. However, its high nephrotoxicity limits its therapeutic application and efficacy. Cisplatin induces nephrotoxicity mainly through oxidative stress and inflammation. Reactive oxygen species (ROS) in the kidneys main...

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Detalles Bibliográficos
Autores principales:	Chen, Ho-Ching, Hou, Hsin-Yu, Sung, Junne-Ming, Shieh, Chi-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040743/ https://www.ncbi.nlm.nih.gov/pubmed/36993800 http://dx.doi.org/10.3389/fmed.2023.1097671

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