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A non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: A randomized controlled trial

The present study aimed to determine the impact of a 10-month multidomain program using dual-task exercise and social activity conducted at a community-based facility on improved cognitive function in older adults with mild to moderate cognitive decline. The participants included 280 community-dwell...

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Autores principales: Lee, Sangyoon, Harada, Kenji, Bae, Seongryu, Harada, Kazuhiro, Makino, Keitaro, Anan, Yuya, Suzuki, Takao, Shimada, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040752/
https://www.ncbi.nlm.nih.gov/pubmed/36993908
http://dx.doi.org/10.3389/fnagi.2023.1005410
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author Lee, Sangyoon
Harada, Kenji
Bae, Seongryu
Harada, Kazuhiro
Makino, Keitaro
Anan, Yuya
Suzuki, Takao
Shimada, Hiroyuki
author_facet Lee, Sangyoon
Harada, Kenji
Bae, Seongryu
Harada, Kazuhiro
Makino, Keitaro
Anan, Yuya
Suzuki, Takao
Shimada, Hiroyuki
author_sort Lee, Sangyoon
collection PubMed
description The present study aimed to determine the impact of a 10-month multidomain program using dual-task exercise and social activity conducted at a community-based facility on improved cognitive function in older adults with mild to moderate cognitive decline. The participants included 280 community-dwelling older adults (age 71–91 years) with mild to moderate cognitive decline. The intervention group exercised for 90 min/day, once a week. Their routine included aerobic exercise and dual-task training which cognitive tasks were performed in combination with exercise. The control group attended health education classes thrice. Before and after the intervention, we measured their cognitive function, physical function, daily conversation, and physical activity. The mean adherence rate of the intervention class was 83.0%. According to a repeated-measures multivariate analysis of covariance in an intent-to-treat analysis, logical memory and 6-min walking distance demonstrated a significant time and group interaction effect. Regarding daily physical activities, we observed significant differences in the daily step count and moderate-to-vigorous physical activity in the intervention group. Our non-pharmacological multidomain intervention resulted in a modest improvement in the cognitive or physical function and building health behavior. It may be a helpful program with a potential role in preventing dementia. Clinical Trial Registration: http://clinicaltrials.gov Identifier ID: UMIN000013097.
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spelling pubmed-100407522023-03-28 A non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: A randomized controlled trial Lee, Sangyoon Harada, Kenji Bae, Seongryu Harada, Kazuhiro Makino, Keitaro Anan, Yuya Suzuki, Takao Shimada, Hiroyuki Front Aging Neurosci Aging Neuroscience The present study aimed to determine the impact of a 10-month multidomain program using dual-task exercise and social activity conducted at a community-based facility on improved cognitive function in older adults with mild to moderate cognitive decline. The participants included 280 community-dwelling older adults (age 71–91 years) with mild to moderate cognitive decline. The intervention group exercised for 90 min/day, once a week. Their routine included aerobic exercise and dual-task training which cognitive tasks were performed in combination with exercise. The control group attended health education classes thrice. Before and after the intervention, we measured their cognitive function, physical function, daily conversation, and physical activity. The mean adherence rate of the intervention class was 83.0%. According to a repeated-measures multivariate analysis of covariance in an intent-to-treat analysis, logical memory and 6-min walking distance demonstrated a significant time and group interaction effect. Regarding daily physical activities, we observed significant differences in the daily step count and moderate-to-vigorous physical activity in the intervention group. Our non-pharmacological multidomain intervention resulted in a modest improvement in the cognitive or physical function and building health behavior. It may be a helpful program with a potential role in preventing dementia. Clinical Trial Registration: http://clinicaltrials.gov Identifier ID: UMIN000013097. Frontiers Media S.A. 2023-03-13 /pmc/articles/PMC10040752/ /pubmed/36993908 http://dx.doi.org/10.3389/fnagi.2023.1005410 Text en Copyright © 2023 Lee, Harada, Bae, Harada, Makino, Anan, Suzuki and Shimada. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Aging Neuroscience
Lee, Sangyoon
Harada, Kenji
Bae, Seongryu
Harada, Kazuhiro
Makino, Keitaro
Anan, Yuya
Suzuki, Takao
Shimada, Hiroyuki
A non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: A randomized controlled trial
title A non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: A randomized controlled trial
title_full A non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: A randomized controlled trial
title_fullStr A non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: A randomized controlled trial
title_full_unstemmed A non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: A randomized controlled trial
title_short A non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: A randomized controlled trial
title_sort non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: a randomized controlled trial
topic Aging Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040752/
https://www.ncbi.nlm.nih.gov/pubmed/36993908
http://dx.doi.org/10.3389/fnagi.2023.1005410
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