ALDH2 attenuates myocardial pyroptosis through breaking down Mitochondrion-NLRP3 inflammasome pathway in septic shock

Cell survival or death is critical for cardiac function. Myocardial pyroptosis, as a newly recognized programmed cell death, remains poorly understood in sepsis. In this study, we evaluated the effect of aldehyde dehydrogenase (ALDH2) on myocardial pyroptosis and revealed the underlying mechanisms i...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Lv, Ying, Zhang, Qingju, Wang, Xingfang, Han, Qi, Liang, Yan, He, Simeng, Yuan, Qiuhuan, Zheng, Jiaqi, Xu, Changchang, Zhang, Xiangxin, Wang, Zichen, Yu, Huaxiang, Xue, Li, Wang, Jiali, Xu, Feng, Pang, Jiaojiao, Chen, Yuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040788/
https://www.ncbi.nlm.nih.gov/pubmed/36992838
http://dx.doi.org/10.3389/fphar.2023.1125866

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