Vitamin B12 attenuates leukocyte inflammatory signature in COVID-19 via methyl-dependent changes in epigenetic markings

COVID-19 induces chromatin remodeling in host immune cells, and it had previously been shown that vitamin B12 downregulates some inflammatory genes via methyl-dependent epigenetic mechanisms. In this work, whole blood cultures from moderate or severe COVID-19 patients were used to assess the potenti...

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Detalles Bibliográficos
Autores principales: Cassiano, Larissa M. G., Cavalcante-Silva, Vanessa, Oliveira, Marina S., Prado, Bárbara V. O., Cardoso, Cristianne G., Salim, Anna C. M., Franco, Gloria R., D’Almeida, Vânia, Francisco, Saionara C., Coimbra, Roney S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040807/
https://www.ncbi.nlm.nih.gov/pubmed/36993968
http://dx.doi.org/10.3389/fimmu.2023.1048790

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