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Palladium-catalyzed asymmetric three-component reaction between glyoxylic acid, sulfonamides and arylboronic acids for the synthesis of α-arylglycine derivatives

A palladium-catalyzed asymmetric three-component synthesis of α-arylglycine derivatives starting from glyoxylic acid, sulfonamides and arylboronic acids is reported. This novel, operationally simple method offers access to the α-arylglycine scaffold in good yields and enantioselectivities. The utili...

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Detalles Bibliográficos
Autores principales:	Jakob, Bastian, Diehl, Andreas M., Horst, Kathrin, Kelm, Harald, Manolikakes, Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040839/ https://www.ncbi.nlm.nih.gov/pubmed/36993813 http://dx.doi.org/10.3389/fchem.2023.1165618

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