Cargando…

Protection from SARS-CoV-2 Variants by MVAs expressing matched or mismatched S administered intranasally to mice

SARS-CoV-2 vaccines prevent severe disease but are less efficient in averting infection and transmission of variant strains, making it imperative to explore ways of enhancing protection. Use of inbred mice expressing the human SARS-CoV-2 receptor facilitates such investigations. We employed recombin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cotter, Catherine A., Americo, Jeffrey L., Earl, Patricia L., Moss, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040904/ https://www.ncbi.nlm.nih.gov/pubmed/36973267 http://dx.doi.org/10.1038/s41541-023-00645-7

Ejemplares similares

Intranasal inoculation of an MVA-based vaccine induces IgA and protects the respiratory tract of hACE2 mice from SARS-CoV-2 infection
por: Americo, Jeffrey L., et al.
Publicado: (2022)

Interferon α/β Decoy Receptor Encoded by a Variant in the Dryvax Smallpox Vaccine Contributes to Virulence and Correlates with Severe Vaccine Side Effects
por: Liu, Ruikang, et al.
Publicado: (2022)

Comparative live bioluminescence imaging of monkeypox virus dissemination in a wild-derived inbred mouse (Mus musculus castaneus) and outbred African dormouse (Graphiurus kelleni)
por: Earl, Patricia L., et al.
Publicado: (2015)

MVA Vector Vaccines Inhibit SARS CoV-2 Replication in Upper and Lower Respiratory Tracts of Transgenic Mice and Prevent Lethal Disease
por: Liu, Ruikang, et al.
Publicado: (2021)

One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection
por: Liu, Ruikang, et al.
Publicado: (2021)

Genetic studies of the susceptibility of classical and wild-derived inbred mouse strains to monkeypox virus
por: Earl, Patricia L., et al.
Publicado: (2015)

Natural killer cells expanded in vivo or ex vivo with IL-15 overcomes the inherent susceptibility of CAST mice to lethal infection with orthopoxviruses
por: Earl, Patricia L., et al.
Publicado: (2020)

Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb.1 in a small animal model
por: Americo, Jeffrey L., et al.
Publicado: (2023)

Susceptibility of the wild-derived inbred CAST/Ei mouse to infection by orthopoxviruses analyzed by live bioluminescence imaging
por: Americo, Jeffrey L., et al.
Publicado: (2014)

Safety and Pharmacokinetics of Intranasally Administered Heparin
por: Harris, Hannah M., et al.
Publicado: (2022)

Safety and Pharmacokinetics of Intranasally Administered Heparin
por: Harris, Hannah M., et al.
Publicado: (2022)

Novel Nonreplicating Vaccinia Virus Vector Enhances Expression of Heterologous Genes and Suppresses Synthesis of Endogenous Viral Proteins
por: Wyatt, Linda S., et al.
Publicado: (2017)

Pharmacokinetics of Intranasally Administered Dexmedetomidine in Chinese Children
por: Wang, Cheng-Yu, et al.
Publicado: (2019)

An intranasal vaccine durably protects against SARS-CoV-2 variants in mice
por: Hassan, Ahmed O., et al.
Publicado: (2021)

Intranasally administered peptidic viral fusion inhibitor protected hDPP4 transgenic mice from MERS-CoV infection
por: Jiang, Shibo, et al.
Publicado: (2015)

Elimination of A-type inclusion formation enhances cowpox virus replication in mice: Implications for orthopoxvirus evolution
por: Kastenmayer, Robin J., et al.
Publicado: (2014)

Adjuvant-enhanced antibody responses to recombinant proteins correlates with protection of mice and monkeys to orthopoxvirus challenges
por: Fogg, Christiana N., et al.
Publicado: (2007)

Observational study of administering intranasal steroid sprays by healthcare workers
por: de Boer, Marielle, et al.
Publicado: (2020)

IMVAMUNE(®) and ACAM2000(®) Provide Different Protection against Disease When Administered Postexposure in an Intranasal Monkeypox Challenge Prairie Dog Model
por: Keckler, M. Shannon, et al.
Publicado: (2020)

In vivo trafficking and immunostimulatory potential of an intranasally-administered primary dendritic cell-based vaccine
por: Vilekar, Prachi, et al.
Publicado: (2010)

Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques
por: Lee, M. R., et al.
Publicado: (2020)

DNA/MVA HIV-1/AIDS vaccine elicits long-lived vaccinia virus-specific immunity and confers protection against a lethal monkeypox challenge
por: Nigam, Pragati, et al.
Publicado: (2007)

Preparation, characterization, and in vivo evaluation of intranasally administered liposomal formulation of donepezil
por: Al Asmari, Abdulrahman K, et al.
Publicado: (2016)

Intranasal or airborne transmission-mediated delivery of an attenuated SARS-CoV-2 protects Syrian hamsters against new variants
por: Stauft, Charles B., et al.
Publicado: (2023)

Intranasally Administered Adjunctive Dexmedetomidine Reduces Perioperative Anesthetic Requirements in General Anesthesia
por: Wu, Xiang, et al.
Publicado: (2016)

Systemic and Mucosal Antibody Responses to Soluble and Nanoparticle-Conjugated Antigens Administered Intranasally
por: Howe, Savannah E., et al.
Publicado: (2016)

Pharmacokinetics and pharmacodynamics of intranasal and intramuscular administration of naloxone in working dogs administered fentanyl
por: Barr, Ciara A., et al.
Publicado: (2023)

Prophylactic Efficacy of Intranasally Administered HSP Nanoparticles for Treating a Lethal SARS-CoV Infection in BALB/c Mice
por: Barnard, Dale, et al.
Publicado: (2009)

Effectiveness of VSV vectored SARS-CoV-2 spike when administered through intranasal, intramuscular or a combination of both
por: Beitari, Saina, et al.
Publicado: (2023)

Intranasal gene therapy to prevent infection by SARS-CoV-2 variants
por: Sims, Joshua J., et al.
Publicado: (2021)

Intranasally Administered MSC-Derived Extracellular Vesicles Reverse Cisplatin-Induced Cognitive Impairment
por: Milutinovic, Bojana, et al.
Publicado: (2023)

Intranasal type I interferon treatment is beneficial only when administered before clinical signs onset in the SARS-CoV-2 hamster model
por: Bessière, Pierre, et al.
Publicado: (2021)

Comparison of Immunogenicity and Protective Efficacy of PPR Live Attenuated Vaccines (Nigeria 75/1 and Sungri 96) Administered by Intranasal and Subcutaneous Routes
por: Mahapatra, Mana, et al.
Publicado: (2020)

Protective effects of a nanoemulsion adjuvant vaccine (2C-Staph/NE) administered intranasally against invasive Staphylococcus aureus pneumonia
por: Yang, Liu-yang, et al.
Publicado: (2018)

Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys
por: Le Nouën, Cyril, et al.
Publicado: (2022)

Enhancing Patient Choice: Using Self-administered Intranasal Naloxone for Novel Rapid Buprenorphine Initiation
por: Randall, Adam, et al.
Publicado: (2023)

The effect of bovine vaccines against respiratory viruses administered either intranasal or intramuscular on broncho-alveolar fluid cells of heifers
por: Rossi, Patricia S., et al.
Publicado: (2021)

Advancing the match-mismatch framework for large herbivores in the Arctic: Evaluating the evidence for a trophic mismatch in caribou
por: Gustine, David, et al.
Publicado: (2017)

Cationic crosslinked carbon dots-adjuvanted intranasal vaccine induces protective immunity against Omicron-included SARS-CoV-2 variants
por: Lei, Hong, et al.
Publicado: (2023)

A next-generation intranasal trivalent MMS vaccine induces durable and broad protection against SARS-CoV-2 variants of concern
por: Xu, Jiayu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_eqt2ckoreva0a5jl92n4oko11a