Truncating PICK1 Variant Identified in Azoospermia Affected Mitochondrial Dysfunction in Knockout Mice

OBJECTIVE: The protein interacting with C kinase 1 (PICK1) plays a critical role in vesicle trafficking, and its deficiency in sperm cells results in abnormal vesicle trafficking from Golgi to acrosome, which eventually disrupts acrosome formation and leads to male infertility. METHODS: An azoosperm...

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Detalles Bibliográficos
Autores principales: Du, Yao-qiang, Shu, Chong-yi, Zheng, Min, Xu, Wei-de, Sun, Yue, Shen, Lu, Zhang, Chen, Zhang, Yu-xin, Wang, Qian-ni, Li, Kai-qiang, Chen, Bing-yu, Hao, Ke, Lyu, Jian-xin, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Huazhong University of Science and Technology 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040929/
https://www.ncbi.nlm.nih.gov/pubmed/36971977
http://dx.doi.org/10.1007/s11596-023-2704-y

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