Intrinsic STING Switches off Pathogenetic Programs of Th1 Cells to Inhibit Colitis

BACKGROUND & AIMS: T helper 1 (Th1) effector cells are implicated in inflammatory bowel disease. The stimulator of interferon genes (STING), an intracellular DNA sensor, has been shown to regulate infection and various cancers. However, whether and how intrinsic STING signaling in Th1 cells regu...

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Detalles Bibliográficos
Autores principales: Yang, Wenjing, Yu, Tianming, Zhou, Guangxi, Yao, Suxia, Wakamiya, Maki, Hu, Haitao, Paessler, Slobodan, Sun, Jiaren, Cong, Yingzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040963/
https://www.ncbi.nlm.nih.gov/pubmed/36736893
http://dx.doi.org/10.1016/j.jcmgh.2023.01.010

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