Heat shock potentiates aminoglycosides against gram-negative bacteria by enhancing antibiotic uptake, protein aggregation, and ROS

The potentiation of antibiotics is a promising strategy for combatting antibiotic-resistant/tolerant bacteria. Herein, we report that a 5-min sublethal heat shock enhances the bactericidal actions of aminoglycoside antibiotics by six orders of magnitude against both exponential- and stationary-phase...

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Detalles Bibliográficos
Autores principales: Lv, Boyan, Huang, Xuebing, Lijia, Chenchen, Ma, Yuelong, Bian, Mengmeng, Li, Zhongyan, Duan, Juan, Zhou, Fang, Yang, Bin, Qie, Xingwang, Song, Yizhi, Wood, Thomas K., Fu, Xinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041086/
https://www.ncbi.nlm.nih.gov/pubmed/36917671
http://dx.doi.org/10.1073/pnas.2217254120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041086/
https://www.ncbi.nlm.nih.gov/pubmed/36917671
http://dx.doi.org/10.1073/pnas.2217254120

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