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Monitoring the compaction of single DNA molecules in Xenopus egg extract in real time
DNA compaction is required for the condensation and resolution of chromosomes during mitosis, but the relative contribution of individual chromatin factors to this process is poorly understood. We developed a physiological, cell-free system using high-speed Xenopus egg extracts and optical tweezers...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041109/ https://www.ncbi.nlm.nih.gov/pubmed/36917660 http://dx.doi.org/10.1073/pnas.2221309120 |