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Monitoring the compaction of single DNA molecules in Xenopus egg extract in real time

DNA compaction is required for the condensation and resolution of chromosomes during mitosis, but the relative contribution of individual chromatin factors to this process is poorly understood. We developed a physiological, cell-free system using high-speed Xenopus egg extracts and optical tweezers...

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Detalles Bibliográficos
Autores principales: Sun, Mingxuan, Amiri, Hossein, Tong, Alexander B., Shintomi, Keishi, Hirano, Tatsuya, Bustamante, Carlos, Heald, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041109/
https://www.ncbi.nlm.nih.gov/pubmed/36917660
http://dx.doi.org/10.1073/pnas.2221309120

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