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Functional SARS-CoV-2 cross-reactive CD4(+) T cells established in early childhood decline with age

Pre-existing SARS-CoV-2-reactive T cells have been identified in SARS-CoV-2-unexposed individuals, potentially modulating COVID-19 and vaccination outcomes. Here, we provide evidence that functional cross-reactive memory CD4(+) T cell immunity against severe acute respiratory syndrome coronavirus 2...

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Detalles Bibliográficos
Autores principales:	Humbert, Marion, Olofsson, Anna, Wullimann, David, Niessl, Julia, Hodcroft, Emma B., Cai, Curtis, Gao, Yu, Sohlberg, Ebba, Dyrdak, Robert, Mikaeloff, Flora, Neogi, Ujjwal, Albert, Jan, Malmberg, Karl-Johan, Lund-Johansen, Fridtjof, Aleman, Soo, Björkhem-Bergman, Linda, Jenmalm, Maria C., Ljunggren, Hans-Gustaf, Buggert, Marcus, Karlsson, Annika C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041119/ https://www.ncbi.nlm.nih.gov/pubmed/36917669 http://dx.doi.org/10.1073/pnas.2220320120

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