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Autolysin-mediated peptidoglycan hydrolysis is required for the surface display of Staphylococcus aureus cell wall-anchored proteins

Peptidoglycan hydrolases, or autolysins, play a critical role in cell wall remodeling and degradation, facilitating bacterial growth, cell division, and cell separation. In Staphylococcus aureus, the so-called “major” autolysin, Atl, has long been associated with host adhesion; however, the molecula...

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Detalles Bibliográficos
Autores principales: Leonard, Allison C., Goncheva, Mariya I., Gilbert, Stephanie E., Shareefdeen, Hiba, Petrie, Laurenne E., Thompson, Laura K., Khursigara, Cezar M., Heinrichs, David E., Cox, Georgina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041135/
https://www.ncbi.nlm.nih.gov/pubmed/36920922
http://dx.doi.org/10.1073/pnas.2301414120