Cargando…

Biocatalytic control of site-selectivity and chain length-selectivity in radical amino acid halogenases

Biocatalytic C–H activation has the potential to merge enzymatic and synthetic strategies for bond formation. Fe(II)/αKG-dependent halogenases are particularly distinguished for their ability both to control selective C–H activation as well as to direct group transfer of a bound anion along a reacti...

Descripción completa

Detalles Bibliográficos
Autores principales: Kissman, Elijah N., Neugebauer, Monica E., Sumida, Kiera H., Swenson, Cameron V., Sambold, Nicholas A., Marchand, Jorge A., Millar, Douglas C., Chang, Michelle C. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041140/
https://www.ncbi.nlm.nih.gov/pubmed/36913566
http://dx.doi.org/10.1073/pnas.2214512120