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Biocatalytic control of site-selectivity and chain length-selectivity in radical amino acid halogenases
Biocatalytic C–H activation has the potential to merge enzymatic and synthetic strategies for bond formation. Fe(II)/αKG-dependent halogenases are particularly distinguished for their ability both to control selective C–H activation as well as to direct group transfer of a bound anion along a reacti...
Autores principales: | Kissman, Elijah N., Neugebauer, Monica E., Sumida, Kiera H., Swenson, Cameron V., Sambold, Nicholas A., Marchand, Jorge A., Millar, Douglas C., Chang, Michelle C. Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041140/ https://www.ncbi.nlm.nih.gov/pubmed/36913566 http://dx.doi.org/10.1073/pnas.2214512120 |
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