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Clinico-pathological study among COVID-19 patients during the second wave of COVID-19 pandemic in Andaman Nicobar Island- “A retrospective cross-sectional study”
BACKGROUND: Andaman and Nicobar Islands, a Union Territory of India is Tropical Island, has better air quality and since its specific geographic location that may have an impact on the clinical and pathological features. So, this study is intended to describe the clinical and pathological features o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041307/ https://www.ncbi.nlm.nih.gov/pubmed/36993058 http://dx.doi.org/10.4103/jfmpc.jfmpc_1106_22 |
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author | Zumu, Mhasisielie Padhy, Prodeep K. Choudhury, Sampa Shail, Kausheen Singh, Mairaj M. Thomas, Beeson |
author_facet | Zumu, Mhasisielie Padhy, Prodeep K. Choudhury, Sampa Shail, Kausheen Singh, Mairaj M. Thomas, Beeson |
author_sort | Zumu, Mhasisielie |
collection | PubMed |
description | BACKGROUND: Andaman and Nicobar Islands, a Union Territory of India is Tropical Island, has better air quality and since its specific geographic location that may have an impact on the clinical and pathological features. So, this study is intended to describe the clinical and pathological features of COVID-19 infection and its association with the severity of the disease among adult COVID-19 patients. MATERIAL AND METHOD: A cross-sectional study done retrospectively among 100 adult COVID-19 RT PCR positive in Tertiary Hospital, tropical Islands by reviewing medical records. The clinical, laboratory parameters were assessed. RESULTS: In the study 65% of the population were male, and 55% of COVID-19 cases were between the age group of 25 to 50 years of age. At presentation, 96% had respiratory symptoms, 91% had fever, 33% had gastrointestinal symptoms, 10% had musculoskeletal symptoms, and 6% have a history of contact with COVID-19 positive patients. The severe COVID-19 patients had longer duration of fever (P-value 0.041), duration of cough (P 0.016), duration of breathlessness (P 0.002), high pulse rate (P = 0.031) at presentation, had high neutrophil/lymphocyte ratio (P = 0.001), high neutrophil count (P < 0.001), low lymphocyte count (P < 0.001), high CRP (P < 0.001), and high D-dimer (P < 0.001) at presentation. CONCLUSION: Severe COVID-19 patients at presentation had longer duration of fever, cough, and breathlessness, hence should seek early medical care. Lab parameters is a great tool in the assessment of patient who can go to have severe disease and thus help in formulating Guidelines. |
format | Online Article Text |
id | pubmed-10041307 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-100413072023-03-28 Clinico-pathological study among COVID-19 patients during the second wave of COVID-19 pandemic in Andaman Nicobar Island- “A retrospective cross-sectional study” Zumu, Mhasisielie Padhy, Prodeep K. Choudhury, Sampa Shail, Kausheen Singh, Mairaj M. Thomas, Beeson J Family Med Prim Care Original Article BACKGROUND: Andaman and Nicobar Islands, a Union Territory of India is Tropical Island, has better air quality and since its specific geographic location that may have an impact on the clinical and pathological features. So, this study is intended to describe the clinical and pathological features of COVID-19 infection and its association with the severity of the disease among adult COVID-19 patients. MATERIAL AND METHOD: A cross-sectional study done retrospectively among 100 adult COVID-19 RT PCR positive in Tertiary Hospital, tropical Islands by reviewing medical records. The clinical, laboratory parameters were assessed. RESULTS: In the study 65% of the population were male, and 55% of COVID-19 cases were between the age group of 25 to 50 years of age. At presentation, 96% had respiratory symptoms, 91% had fever, 33% had gastrointestinal symptoms, 10% had musculoskeletal symptoms, and 6% have a history of contact with COVID-19 positive patients. The severe COVID-19 patients had longer duration of fever (P-value 0.041), duration of cough (P 0.016), duration of breathlessness (P 0.002), high pulse rate (P = 0.031) at presentation, had high neutrophil/lymphocyte ratio (P = 0.001), high neutrophil count (P < 0.001), low lymphocyte count (P < 0.001), high CRP (P < 0.001), and high D-dimer (P < 0.001) at presentation. CONCLUSION: Severe COVID-19 patients at presentation had longer duration of fever, cough, and breathlessness, hence should seek early medical care. Lab parameters is a great tool in the assessment of patient who can go to have severe disease and thus help in formulating Guidelines. Wolters Kluwer - Medknow 2022-11 2022-12-16 /pmc/articles/PMC10041307/ /pubmed/36993058 http://dx.doi.org/10.4103/jfmpc.jfmpc_1106_22 Text en Copyright: © 2022 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Zumu, Mhasisielie Padhy, Prodeep K. Choudhury, Sampa Shail, Kausheen Singh, Mairaj M. Thomas, Beeson Clinico-pathological study among COVID-19 patients during the second wave of COVID-19 pandemic in Andaman Nicobar Island- “A retrospective cross-sectional study” |
title | Clinico-pathological study among COVID-19 patients during the second wave of COVID-19 pandemic in Andaman Nicobar Island- “A retrospective cross-sectional study” |
title_full | Clinico-pathological study among COVID-19 patients during the second wave of COVID-19 pandemic in Andaman Nicobar Island- “A retrospective cross-sectional study” |
title_fullStr | Clinico-pathological study among COVID-19 patients during the second wave of COVID-19 pandemic in Andaman Nicobar Island- “A retrospective cross-sectional study” |
title_full_unstemmed | Clinico-pathological study among COVID-19 patients during the second wave of COVID-19 pandemic in Andaman Nicobar Island- “A retrospective cross-sectional study” |
title_short | Clinico-pathological study among COVID-19 patients during the second wave of COVID-19 pandemic in Andaman Nicobar Island- “A retrospective cross-sectional study” |
title_sort | clinico-pathological study among covid-19 patients during the second wave of covid-19 pandemic in andaman nicobar island- “a retrospective cross-sectional study” |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041307/ https://www.ncbi.nlm.nih.gov/pubmed/36993058 http://dx.doi.org/10.4103/jfmpc.jfmpc_1106_22 |
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