MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis

We previously demonstrated that antisense oligonucleotide-mediated knockdown of Mboat7, the gene encoding membrane bound O-acyltransferase 7, in the liver and adipose tissue of mice promoted high fat diet-induced hepatic steatosis, hyperinsulinemia, and systemic insulin resistance. Thereafter, other...

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Detalles Bibliográficos
Autores principales: Massey, William J., Varadharajan, Venkateshwari, Banerjee, Rakhee, Brown, Amanda L., Horak, Anthony J., Hohe, Rachel C., Jung, Bryan M., Qiu, Yunguang, Chan, E. Ricky, Pan, Calvin, Zhang, Renliang, Allende, Daniela S., Willard, Belinda, Cheng, Feixiong, Lusis, Aldons J., Brown, J. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041558/
https://www.ncbi.nlm.nih.gov/pubmed/36806709
http://dx.doi.org/10.1016/j.jlr.2023.100349

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