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Evaluation of Radiation Sensitivity Differences in Mouse Liver Tumor Organoids Using CRISPR/Cas9-Mediated Gene Mutation

BACKGROUND: To assess the radiosensitivity of liver tumors harboring different genetic mutations, mouse liver tumors were generated in vivo through the hydrodynamic injection of clustered regularly interspaced short palindromic repeat/caspase 9 (CRISPR/Cas9) constructs encoding single-guide RNAs (sg...

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Detalles Bibliográficos
Autores principales:	Jeon, Wan, Jung, Se Yeon, Lee, Chae Young, Kim, Won-Tae, Kim, Hyun, Jang, Kyoung Won, Lim, Heuijin, Lee, Manwoo, Jeong, Dong Hyeok, Kim, Sung Dae, Kim, In Ah, Choi, Si Ho, Son, Tae Gen, Kim, Kyung Su
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041602/ https://www.ncbi.nlm.nih.gov/pubmed/36960537 http://dx.doi.org/10.1177/15330338231165125

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